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It is recycled back into methionine through a pathway that involves vitamin B12 in the form of methylcobalamin (which remethylates it) and folate. Homocysteine is simply an intermediate in a very important biochemical pathway. Plasma homocysteine can also travel another route which involves the passing of sulfur groups (transsulfuration). This is vitamin B6-dependent and results in the production of cysteine which can convert into glutathione, the most important antioxidant in the body.
Homocysteine Levels Need To be tested Twice Per Year When:-
Testing For Deficiencies Of Folate, B6 and B12
Elevations of any of these markers on the CMP test may increase risk of homocysteinemia. Patients with hypothyroidism are at greater risk of hyperhomocysteinemia because hypothyroidism decreases hepatic levels of enzymes involved in the remethylation pathway of homocysteine.
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Methylation Protect contains key nutrients that help maintain a healthy homocysteine pathway, allowing for the normal production of necessary and important end products. This formulation includes Folate, a proprietary blend of naturally occurring folates known to facilitate the efficient metabolism of homocysteine. These include the sulfur-containing amino acids taurine and cysteine, and the neurotransmitters norepinephrine and dopamine. The mineral zinc is also included in this formulation, because it is a necessary cofactor for the proper support of enzymes in the pathway.
Homocysteine Become Elevated Due To:-
Any roadblock in this pathway can cause homocysteine to elevate. When we intricately study the biochemistry of the homocysteine pathway we can see that it involves a series of conversions that require enzymes. Several nutrients, especially B vitamins, are needed for these conversions to occur. Stress can deplete B vitamins, as can many medications.
It is important to check B vitamin levels and also test the body's homocysteine levels. Performing both tests on women wishing to get pregnant could reduce the risk of neural tube defects and pregnancy complications. All patients with homocysteine levels above 7 micromol/L are in need of intervention with Methylation Protect being an ideal recommendation. Patients with a family history of early heart attacks or depression are also prime candidates for such intervention.
|0-6.9 micromol/L||Optimum (low risk)|
|7 - 9.9 micromol/L||Mild risk|
|10.- 12.9 micromol/L||Moderate Risk|
|13 - 20 micromol/L||High risk|
|Over 20 micromol/L||Very high risk|
Methylation Protect is a comprehensive formula designed to support optimal methylation and help maintain healthy homocysteine levels already within normal range. It features six key nutrients that are involved in homocysteine metabolism: folate as calcium folinate and Quatrefolic® for increased bioactivity; trimethylglycine; vitamins B12, B6, and B2 and NAC. These six nutrients, provided in activated forms, support enhanced methylation and overall cardiovascular health. Homocysteine is produced by the demethylation of dietary methionine which comes from protein containing foods.
Homocysteine levels is an Independent Risk Factor for Hardening of:-
Excess homocysteine in the circulation can damage the lining of arterial walls, making them narrow and inelastic.
Elevated Homocysteine Is Linked with A Number Of Other Serious Medical Conditions Including:-
When homocysteine is elevated it reduces nitric oxide (NO) production, which can increase the risk of hypertension and erectile dysfunction. The synergistic nutrients included in Methylation Protect facilitate the efficient metabolism of homocysteine, and prevent toxic levels of homocysteine from accumulating. Methylation Protect allows the homocysteine pathway (which begins with methionine) to flow smoothly in any direction, producing its necessary and important end products, including the sulfur-containing amino acids taurine and cysteine and the neurotransmitters epinephrine, dopamine, and serotonin.
Methylation Protect will Support:-
*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. The information contained herein is for informational purposes only and does not establish a doctor-patient relationship. Please be sure to consult your physician before taking this or any other product. Consult your physician for any health problems.
Made with non-GMO ingredients.
Manufactured in a GMP Registered Facility in the USA
Product Size: 120 vegetarian capsules
Servings Per Container: 60
Notice: Color, Size or Shape May Appear Different Between Lots
Homocysteine Levels Tend To Rise With:-
Methylation Protect includes Quatrefolic® blend of active isomer, naturally-occuring folates. Research shows that supplementing 2-7 mg of folates daily helps to reverse plaque and prevent stroke.Research also shows that doses above 1000 mcg of B12 get absorbed effectively even without intrinsic factor.